The CTC1-STN1-TEN1 (CST) complex is a single-strand DNA-binding protein complex that plays an important role in genome maintenance in various model eukaryotes.Dysfunction of CST is the underlying cause of the rare genetic disorder known as Coats plus disease.In addition, down regulation of STN1 promotes colorectal cancer development in mice.While p
Early human placental development begins with blastocyst implantation, then the trophoblast differentiates and originates the cells required for a proper fetal nutrition and placental implantation.Among them, extravillous trophoblast corresponds to a non-proliferating trophoblast highly invasive that allows the vascular remodeling which is essentia
Abstract: CD34 is routinely used to identify and isolate human hematopoietic stem/progenitor cells (HSPCs) for use clinically in bone marrow transplantation, but its function on these cells remains elusive.Glycoprotein ligands on HSPCs help guide their migration to specialized microvascular beds in the bone marrow that express vascular selectins (E
Abstract Objectives To describe the presentation, work-up, and management of patients with metastatic renal cell carcinoma (RCC) to the sinonasal cavity and skull base, and to describe our current cbb5 treatment algorithm of endoscopic surgical resection followed by radiation therapy.Design Retrospective review of two recent cases from our institut
Objectives The aim of this cross-sectional study was to determine the life satisfaction of older people living in a home environment and to find out what predictors influence it.Methods The research involved 1,121 older people 60 years and above from the Moravian-Silesian region who live in a home environment.The short form of the Life Satisfaction